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Ideal candidates are research models with metabolic dysfunction characterized by both impaired insulin sensitivity and elevated adipose tissue NNMT expression common in diet-induced obesity, age-related metabolic decline, and type 2 diabetes models
At least 176 distinct O-antigen structures have been identified in E
This phenomenon is exacerbated by the agerelated decline in the efficiency of the antioxidant system, which becomes insufficient to neutralize excess ROS, leading to oxidative stress and subsequent tissue damage [31]
The statistics are compelling: worldwide, nearly 4 million people die each year due to overweight or obesity-related causes, highlighting the pressing need for innovative solutions
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